Lionel Messi is bidding to score at home in the Champions League for the first time this season as Barcelona take on Borussia Dortmund.
The Argentina international fired his latest blank in the 0-0 draw with Slavia Prague three weeks ago, leaving his side with work to do if they are to progress to the last 16.
Barca will be through if they beat Dortmund or if they draw and Inter fall to defeat at Slavia in the other Group F contest taking place on Wednesday.
Elsewhere, holders Liverpool host Napoli at Anfield aiming to avenge a 2-0 defeat from the reverse fixture, while Chelsea will reach the knockout stages with victory against Valencia.
Below, we have highlighted the key data ahead of Wednesday s eight matches.
Barcelona v Borussia Dortmund
12 Barcelona forward Messi scored with his last shot at Camp Nou in the 2018-19 Champions League season. He has attempted 12 without success this term, failing to score in both home matches. Should he not to score in this game, it would be first time since October 2011 he has failed to find the back of the net in three consecutive home games in the competition (a run of four).
4 Borussia Dortmund s Achraf Hakimi has scored four Champions League goals this season – only one Moroccan player has ever netted more in a single campaign, with Marouane Chamakh scoring five for Bordeaux in the 2009-10 campaign.
Elegantly sipping, with
— FC Barcelona (@FCBarcelona)
Slavia Prague v Inter
3,119 Slavia Prague have given 3,119 minutes to Czech players in the Champions League this season – the most by players of the nation of the club they are representing in the competition this campaign.
3 Lautaro Martinez has scored in his last three Champions League appearances for Inter. He could become the fifth Argentinian to score in four consecutively, after Hernan Crespo (2002), Lionel Messi (six occasions), Sergio Aguero (2019) and Ezequiel Lavezzi (2013).
Liverpool v Napoli
2 Liverpool s Alex Oxlade-Chamberlain has scored in his last two Champions League appearances – the only Englishman to score in three consecutive matches for the Reds is Steven Gerrard (five in a row in 2007-08).
3 Napoli head coach Carlo Ancelotti was the last manager to win an away Champions League match at Anfield, leading Real Madrid to a 3-0 victory in October 2014. No coach has won more away Champions League games in England than Ancelotti (three – level with Jose Mourinho and Massimiliano Allegri).
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— Liverpool FC (@LFC)
Genk v Salzburg
0 Genk remain winless in all 16 of their Champions League matches (W0 D8 L8). It is the fifth longest winless run in the competition s history and the longest since December 2017 (Maribor – 17 matches).
5 Salzburg striker Erling Haaland will become just the third player to score in his first five Champions League appearances if he scores in this match. The two to do so are Alessandro Del Piero (1995, Juventus) and Diego Costa (2013-14, Atletico Madrid).
Valencia v Chelsea
3 Valencia have won three of their last four home Champions League games (W3 D0 L1), having lost four of their previous five (W1 D0 L4).
14 Chelsea striker Tammy Abraham has had more shots than any other Chelsea player in the Champions League this season (14). However, he has found the net with just one of those shots and has scored as many own goals as he has goals (one).
More action on the way this week!
— Chelsea FC (@ChelseaFC)
Lille v Ajax
10 Lille are winless in 10 home Champions League matches (W0 D4 L6). Only two teams have ever had longer home winless runs – Spartak Moscow (11 between 2001 and 2006) and Steaua Bucharest (13 between 1996 and 2013).
10 Ajax s Hakim Ziyech has been involved in 10 goals in his last 12 Champions League appearances (four goals, six assists). The Moroccan has either scored or assisted in each of his last six away games in the competition (two goals, five assists).
RB Leipzig v Benfica
30 RB Leipzig are one of only two teams yet to give a single minute to a player aged 30+ in the Champions League this season, along with Genk. In his 10 games as coach in the competition, Julian Nagelsmann has only used one player aged 30 or older – Hungarian striker Adam Szalai for Hoffenheim last season.
10 Benfica have lost all 10 of their away matches in Germany in the European Cup/Champions League, facing six different teams without success.
Attention returns to
Knockout stage qualification up for grabs this Wednesday
— RB Leipzig English (@RBLeipzig_EN)
Zenit v Lyon
2 Zenit have lost two of their last three home European matches (excluding qualifiers) – one more than they had lost in their previous 21 home games (W18 D2 L1).
4 Lyon s Memphis Depay has scored in all four Champions League matches this season. No Lyon player has ever scored in five consecutive appearances, while only three Dutchmen have scored in five or more – Roy Makaay (2002), Ruud van Nistelrooy (2002, 2003 and 2007) and Arjen Robben (2013).